3,4-Dimethoxybenzeneboronic acid, pinacol ester

3,4-Dimethoxybenzeneboronic acid, pinacol ester - Names and Identifiers

Name	3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER
Synonyms	4-DiMethoxyloxyphenyl)-4 2-(3,4-Dimethoxyphenyl)-4,4,5,5-tetramethyl- 3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER 3,4-Dimethoxybenzeneboronic acid, pinacol ester 3,4-DIMETHOXYPHENYLBORONIC ACID, PINACOL ESTER-YL) METHANAMINE 2-(3,4-DIMETHOXYPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE 2-(3,4-DIMETHOXYLOXYPHENYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
CAS	365564-10-9

3,4-Dimethoxybenzeneboronic acid, pinacol ester - Physico-chemical Properties

Molecular Formula	C14H23BO5
Molar Mass	282.14
Density	1.05±0.1 g/cm3(Predicted)
Melting Point	86-87°C
Boling Point	352.5±32.0 °C(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

3,4-Dimethoxybenzeneboronic acid, pinacol ester - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes
Safety Description	S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3

3,4-Dimethoxybenzeneboronic acid, pinacol ester - Introduction

3,4-dimethoxyphenylboronic ACID, PINACOL ESTER is an organic compound with the chemical formula C10H15BO4. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 3,4-dimethoxyphenylboronic ACID, PINACOL ESTER is a colorless crystalline solid.
-Solubility: It can be dissolved in polar organic solvents (such as dimethyl sulfoxide, dimethylformamide and acetonitrile), but it has poor solubility in non-polar solvents.
-Melting point: Its melting point is about 65-70 ° C.
-Stability: 3,4-dimethoxyphenylboronic ACID, PINACOL ESTER can be stored stably at room temperature, but light and moisture should be avoided.

Use:
-3,4-dimethoxyphenyboronic ACID, PINACOL ESTER is an important organic synthesis intermediate, widely used in organic chemical reactions.
-It is often used as a substrate and reagent for palladium-catalyzed coupling reactions (such as Suzuki coupling reaction, Heck coupling reaction, Sonogashira coupling reaction, etc.).
-In addition, it can also be used to prepare various drugs, organic photoelectric materials and ligands.

Method:
3,4-dimethoxylboronic ACID, PINACOL ESTER is mainly prepared by reacting 3,4-dimethoxylboronic ACID with PINACOL under alkaline conditions to generate corresponding esterification products.

Safety Information:
-3,4-dimethoxyphenylboronic ACID, PINACOL ESTER is generally stable and safe under normal use conditions.
-However, because it is an organic compound, care should be taken to avoid contact with skin, eyes and inhalation during handling or storage.
-Use appropriate personal protective equipment such as lab gloves, goggles and protective masks when handling.
-In the event of accidental contact or inhalation, wash the affected area immediately and seek medical assistance.

Last Update：2024-04-09 20:44:15